In Nepatica Joint and Bone Combo we have mixed together the most powerful ingredients to help and support our joints and bones. It is Glucosamine (300 mg), Yucca root (300 mg),Chondroitin Sulfate (200 mg), Rose hip (150 mg), Boswellia (100 mg), Horsetail (100 mg) and Flaxseed (80 mg)

Glucosamine is a natural substance in the human body. It provides strength, flexibility, and elasticity to cartilage and connective tissue by stimulating the production of glycosaminoglycans, molecules that hold joint tissue together. Glucosamine also decreases inflammation that can lead to the joint destruction of arthritis. Glucosamine is a form of amino sugar that plays a role in cartilage formation and repair. Because glucosamine works from within, bathing the joints in a proverbial warm and protective solution and working to heal the joints instead of merely cover up pain, results take a little bit longer than with NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Glucosamine works to protect the joints from further damage while continuing to stave off further damage. Contrasted to glucosamine, there is evidence that many of the NSAIDs can actually work against arthritic joints, to cause arthritis pain to become even worse by breaking down the joints.

Yucca root also known as manioc or cassava is a tropical vegetable commonly grown and consumed in Africa, Asia, Latin America, and the Caribbean. In many countries, yucca root is a dietary staple usually eaten boiled or steamed. Yucca root is also used as an herbal remedy to relieve inflammation. Yucca root has a long history of use to reduce pain and inflammation caused by arthritis and rheumatism. Yucca root can also reduce joint inflammation. A constituent of the yucca called a phytosterol is responsible for its anti-inflammatory properties. Yucca root is used as an herbal remedy to relieve inflammation. Yucca root also relieves pain associated with arthritis and joint pain due to the saponins in the plant. Yucca contains a high level of steroid saponins (natural glucosides). Saponin is a natural pain killer and is the precursor to cortisone.

Chondroitin Sulfate is another substance found naturally in the body. It is an important element in the creation of cartilage.The Chondroitin Sulfate attracts water to the proteoglycans, which is a vital part of maintaining healthy joint cartilage.

Rose hips provide new ways of tackling many inflammatory diseases such as arthritis. The red berries, one of the richest sources of vitamin C, have been used in cooking and medicine for hundreds of years, but more recently rose hip extract has been shown to reduce pain and improve movement in patients with osteoporosis (a form of arthritis).Experts now believe that rose hip also can combat rheumatoid arthritis, Crohn's disease and even heart disease. All are conditions in which inflammation plays an important role. Rheumatoid arthritis is an autoimmune disease and more serious than osteoarthritis, which is caused by wears and tears of the joints. Inflammation is now known to be a key element of the process that leads to hardening and narrowing of the arteries. Laboratory tests have shown that rose hip inhibits the migration of white blood cells to sites of tissue damage, which fuels inflammation. Antioxidants in the rosehip powder may also neutralize toxic substances released by the white blood cells. Rose hip shows that it increases joint mobility for arthritis sufferers, including morning joint stiffness on waking, manage joint pain, relieve arthritic pain, and even improve sleep when it is affected by joint pain and discomfort.

Boswella (Boswellia serrata) is also known as boswellin or "Indian frankincense," comes from the Boswellia serrata tree. Boswellia. serrata is a large branching tree that grows in the hilly regions of India. Research has identified specific active anti-inflammatory ingredients in Boswellia, which are commonly referred to as boswellic acids. In studies, these acids have been shown to significantly decrease inflammation in several ways. Boswella appears to be able to inhibit inflammation by blocking the synthesis of leukotrienes. Leukotrienes cause inflammation by promoting free radical damage, calcium dislocation, autoimmune responses, cell adhesion and the migration of inflammation-producing cells to the inflamed body area. They improve blood flow to the joints. Boswellia can help to: ease osteoarthritis and rheumatoid arthritis symptoms and decrease back pain. Boswellia's anti-inflammatory properties can help to reduce aching and stiffness.

Horsetail is a perennial plant that is found in or near watery areas such as marshes, streams, or rivers. Horsetail grows in temperate northern hemisphere areas of Asia, Europe, North America, and North Africa. It flourishes where it can root in water or clay soil. Horsetail is a derivative of larger plants that grew 270 million years ago during the carboniferous period. It belongs to the Equisetaceae family and is a relative of the fern. Horsetail is rich in minerals, particularly silica deposited in its stems. Silica helps to promote the body's absorption of calcium, an important component in tissue repair and bone and cartilage formation. Horsetail's silica and silicic acid content ranges from 5-8%, making it a good source for strengthening weak connective tissues, and healing bones, fractures, and torn ligaments. Horsetail is also used to treat arthritis and osteoporosis, as the silicon in horsetail may replace lost silicon in the affected bones.

Flax seeds have natural anti-inflammatory benefits, which makes them beneficial for persons who suffer from ache in joints and bones. The Omega-3 fatty acids found in flax seeds are used by the body to produce prostaglandins. These are hormone-like substances which help reduce inflammation. Flaxseed is good to ease joint pain, by lubricating the joints. It can reduce the stiffness for arthritis patients.